Tesofensine
Metabolic & Weight ManagementTriple monoamine reuptake inhibitor that promotes significant weight loss and increases energy.
Key Benefits
- ✓Significant weight loss (10-15%)
- ✓Increased energy and motivation
- ✓Enhanced mood
- ✓Appetite suppression
- ✓Improved focus
- ✓Metabolic enhancement
Dosing Information
Detailed Protocol
Taken orally once daily in the morning. Start with lowest dose and increase gradually. Not widely available, investigational.
About Tesofensine
Tesofensine is a presynaptic reuptake inhibitor of serotonin, noradrenaline, and dopamine. Originally developed as a treatment for Alzheimers and Parkinsons, it showed remarkable weight loss effects in trials. Not technically a peptide but often included in peptide discussions for weight loss.
Research Notes
Clinical trials showed 12.8% weight loss at 0.5mg dose over 24 weeks. Development discontinued by major pharma but being pursued by others. Requires cardiovascular monitoring.
Potential Side Effects
- •Increased heart rate
- •Elevated blood pressure
- •Dry mouth
- •Insomnia if taken late
- •Nausea
- •Requires monitoring
Always consult with a healthcare professional before starting any peptide therapy.