Back to Directory
Substance P
Performance & EnduranceNeurotransmitter peptide involved in pain transmission and inflammation.
Key Benefits
- ✓Involved in pain transmission
- ✓Neurotransmitter
- ✓Inflammation mediator
- ✓Target for pain therapies
Dosing Information
Dosage Range
Endogenous
Frequency
Natural
Typical Duration
N/A
Detailed Protocol
Not therapeutically administered - natural neurotransmitter. Antagonists (NK-1 receptor antagonists) used therapeutically for nausea and under investigation for pain.
About Substance P
Substance P is an 11-amino acid neuropeptide that functions as a neurotransmitter and neuromodulator. It is involved in pain transmission, inflammation, and smooth muscle contraction. Antagonists being developed for pain, not peptide itself used therapeutically.
Research Notes
Important in pain pathways. NK-1 receptor antagonists (aprepitant) FDA-approved for chemotherapy-induced nausea. Peptide itself not therapeutic agent.
Potential Side Effects
- •Endogenous peptide
Always consult with a healthcare professional before starting any peptide therapy.