Back to Directory

MK-677 (Ibutamoren)

Growth Hormone Secretagogues

Orally active growth hormone secretagogue that mimics ghrelin, popular for its convenience and sustained GH elevation.

Key Benefits

  • ✓Sustained GH and IGF-1 elevation
  • ✓Increased lean body mass
  • ✓Improved bone density
  • ✓Enhanced sleep quality
  • ✓Increased appetite
  • ✓Oral administration (no injections)
  • ✓Improved skin and hair

Dosing Information

Dosage Range
10-25 mg
Frequency
Once daily
Typical Duration
3-6 months, then cycle off

Detailed Protocol

Taken orally once daily, typically before bed to maximize GH pulse during sleep and minimize daytime hunger. Start with lower doses to assess tolerance.

About MK-677 (Ibutamoren)

MK-677, also known as Ibutamoren, is a non-peptide growth hormone secretagogue that mimics ghrelin. Unlike injectable peptides, it is orally active with a 24-hour half-life, providing sustained elevation of GH and IGF-1 levels. It binds to the ghrelin receptor in the brain.

Research Notes

Extensive research shows MK-677 increases GH and IGF-1 levels for 24+ hours after single dose. Studies demonstrate improvements in body composition, bone density, and sleep quality.

Get Peptide Research Updates

Newsletter signup

Please wait...

Thanks for signing up! You will receive an email to confirm your subscription.

Potential Side Effects

  • •Increased appetite
  • •Water retention
  • •Possible increase in blood glucose
  • •Fatigue
  • •Tingling in extremities

Always consult with a healthcare professional before starting any peptide therapy.