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Enfuvirtide

Performance & Endurance

Fusion inhibitor peptide for HIV treatment, prevents viral entry into cells.

Key Benefits

  • ✓Inhibits HIV fusion
  • ✓For multi-drug resistant HIV
  • ✓Prevents viral entry
  • ✓Used in salvage therapy

Dosing Information

Dosage Range
90 mg
Frequency
Twice daily
Typical Duration
Ongoing

Detailed Protocol

Administered via subcutaneous injection twice daily. Requires reconstitution. Sites rotated to prevent injection site reactions. Prescription only for HIV-positive patients.

About Enfuvirtide

Enfuvirtide (Fuzeon, T-20) is a synthetic 36-amino acid peptide that inhibits HIV-1 fusion with CD4+ cells by binding to the gp41 envelope protein. First fusion inhibitor approved for HIV treatment, used in treatment-experienced patients.

Research Notes

FDA-approved in 2003 as first HIV fusion inhibitor. Effective in treatment-experienced patients with resistant virus. High rate of injection site reactions limits use.

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Potential Side Effects

  • •Very common injection site reactions
  • •Bacterial pneumonia risk
  • •Hypersensitivity reactions
  • •Eosinophilia
  • •Expensive

Always consult with a healthcare professional before starting any peptide therapy.