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Relaxin

Performance & Endurance

Reproductive hormone peptide that softens cervix and has cardiovascular effects being studied.

Key Benefits

  • ✓Softens cervix in pregnancy
  • ✓Vasodilation
  • ✓Antifibrotic effects
  • ✓Studied for heart failure
  • ✓Improves arterial compliance

Dosing Information

Dosage Range
Not currently available
Frequency
Development discontinued
Typical Duration
N/A

Detailed Protocol

Natural hormone during pregnancy. Serelaxin (recombinant relaxin-2) was in development for heart failure but discontinued despite positive trial results.

About Relaxin

Relaxin is a 6-kDa peptide hormone structurally related to insulin. Produced during pregnancy to soften cervix and relax ligaments. Recombinant relaxin studied for acute heart failure and fibrotic diseases. Serelaxin development discontinued despite positive effects.

Research Notes

RELAX-AHF trials showed benefits for acute heart failure but development discontinued. Natural pregnancy hormone. Therapeutic development has been challenging.

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Potential Side Effects

  • •Development of serelaxin discontinued despite efficacy

Always consult with a healthcare professional before starting any peptide therapy.