Insulin NPH
Performance & EnduranceIntermediate-acting human insulin with protamine, historical basal insulin still widely used.
Key Benefits
- ✓Intermediate basal coverage
- ✓12-18 hour duration
- ✓Lower cost than analogs
- ✓Widely available globally
- ✓Twice-daily dosing typically
Dosing Information
Detailed Protocol
Administered subcutaneously typically twice daily before breakfast and dinner. Requires gentle mixing before injection (cloudy suspension). Dose adjusted to glucose patterns.
About Insulin NPH
NPH (Neutral Protamine Hagedorn) insulin is human insulin complexed with protamine to delay absorption, providing intermediate action (12-18 hours). Cloudy suspension requiring mixing. Less expensive than analogs but less predictable.
Research Notes
Developed 1946, still widely used globally due to low cost. Higher hypoglycemia risk and less predictable than modern analogs. Important option for resource-limited settings.
Potential Side Effects
- •Higher hypoglycemia risk than analogs
- •Pronounced peak
- •Weight gain
- •Requires consistent meal timing
Always consult with a healthcare professional before starting any peptide therapy.