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Macimorelin

Growth Hormone Secretagogues

Oral ghrelin receptor agonist used for diagnostic testing of growth hormone deficiency.

Key Benefits

  • ✓Diagnostic test for GH deficiency
  • ✓Orally active
  • ✓Stimulates GH release
  • ✓Safer than insulin tolerance test
  • ✓Convenient single-dose test

Dosing Information

Dosage Range
0.5 mg/kg
Frequency
Single oral dose
Typical Duration
One-time test

Detailed Protocol

Administered orally as a single dose during diagnostic testing. Patient fasts overnight, takes oral solution, then blood drawn at intervals to measure GH response.

About Macimorelin

Macimorelin (Macrilen) is an orally active ghrelin receptor agonist that stimulates GH release. FDA-approved for diagnostic use to test for adult growth hormone deficiency. Oral administration makes it more convenient than insulin tolerance test.

Research Notes

FDA-approved in 2017 for GH deficiency diagnosis. Provides convenient oral alternative to insulin tolerance test. Good safety profile for diagnostic use.

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Potential Side Effects

  • •Dysgeusia (altered taste)
  • •Diarrhea
  • •Upper respiratory infection
  • •Fatigue
  • •Generally well tolerated

Always consult with a healthcare professional before starting any peptide therapy.