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Angiotensin II
Performance & EnduranceVasoconstrictor peptide for refractory hypotension, used in critical care settings.
Key Benefits
- ✓Increases blood pressure
- ✓Treats refractory shock
- ✓Vasoconstriction
- ✓ICU use for hypotension
Dosing Information
Dosage Range
5-40 ng/kg/min
Frequency
Continuous IV infusion
Typical Duration
Until pressure stable
Detailed Protocol
Administered via continuous intravenous infusion through central line in ICU setting. Dose titrated to blood pressure response. Critical care use only.
About Angiotensin II
Angiotensin II (Giapreza) is a synthetic version of the naturally occurring vasoactive peptide. It is a potent vasoconstrictor used to increase blood pressure in adults with distributive shock who remain hypotensive despite fluid and vasopressor therapy.
Research Notes
FDA-approved in 2017 for distributive shock. Reserved for refractory hypotension when other vasopressors insufficient. ICU use only with close monitoring.
Potential Side Effects
- •Thrombosis risk
- •Acidosis
- •Peripheral ischemia
- •Tachycardia
- •Requires ICU monitoring
Always consult with a healthcare professional before starting any peptide therapy.